| Title | : | Theory of Hematopoiesis Control (SpringerBriefs in Cell Biology) |
| Author | : | Alexander Dygai |
| Language | : | en |
| Rating | : | |
| Type | : | PDF, ePub, Kindle |
| Uploaded | : | Apr 03, 2021 |
| Title | : | Theory of Hematopoiesis Control (SpringerBriefs in Cell Biology) |
| Author | : | Alexander Dygai |
| Language | : | en |
| Rating | : | 4.90 out of 5 stars |
| Type | : | PDF, ePub, Kindle |
| Uploaded | : | Apr 03, 2021 |
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Some stability condition and control methods were put forward. authors presented a feedback control method for the global attractivity of a positive almost-periodic solution of the model of hematopoiesis. [14–17], the authors pointed out that the hematopoiesis can be controlled by the gene regulation or drugs.
The monophyletic theory of hematopoiesis states that pluripotent stem cells multiply to produce more pluripotent stem cells, thus ensuring the steady and lasting supply of stem cells. Some of the pluripotent stem cells differentiate into precursor cells that are at least partially committed to become one type of mature blood cell.
This paper is concerned with a time-varying delayed hematopoiesis model with discontinuous harvesting terms. The harvesting terms considered in our hematopoiesis model are discontinuous which are totally different from the previous continuous, lipschitz continuous or even smooth ones. By means of functional differential inclusions theory, inequality technique and the non-smooth analysis theory.
Two models for hematopoiesis have been proposed: determinism and stochastic theory. For the stem cells and other undifferentiated blood cells in the bone marrow, the determination is generally explained by the determinism theory of haematopoiesis, saying that colony stimulating factors and other factors of the haematopoietic microenvironment determine the cells to follow a certain path of cell differentiation.
Blood cells develop from hematopoietic stem cells and are formed in the bone marrow through the highly regulated process of hematopoiesis. Hematopoietic stem cells are capable of transforming into red blood cells, white blood cells, and platelets.
Nov 19, 2019 these initial studies offer a theoretical basis for stiffness-related hsc fate control.
The first theory claims that aging is related to mutations that are related to long-term survival and that aging is related to the accumulation of genetic mutations that are not repaired. Another theory is that aging is related to the late effects of certain genes, and is referred to as pleiotropic antagonism.
All the blood celular components is derived by hematopoietic stem cells.
The sense of control is closely related in opposite ways to power and trust. You can get a sense of control by taking control and acting, which is effectively about power. You can also get a sense of control by ceding it to others, which requires trust.
The mammalian hematopoietic system has long been viewed as a hierarchical paradigm in which a small number of hematopoietic stem cells (hscs) are located at the apex. Hscs were traditionally thought to be homogeneous and quiescent in a homeostatic state. However, recent observations, through extramedullary hematopoiesis and clonal assays, have cast doubt on the validity of the conventional.
Hematopoiesis, hematopoietic stem cells, and aging of hematopoietic stem cells. The mammalian blood system consists of many distinct types of differentiated cells with specialized functions like erythrocytes, platelets, t and b lymphocytes, myeloid cells, mast cells, natural killer cells, and dendritic cells.
Clonal haemopoiesis and therapy-related myeloid malignancies in elderly patients: a proof-of-concept, case-control study.
Hematopoiesis (pronounced heem-at-oh-po-ee-sus) is the process by which all of your blood cells are formed, develop and mature into their final adult types. The term refers to the pathways or tracks of blood cell development, beginning with what’s known as a hematopoietic stem cell (hsc), going through a series of steps to arrive at the final product—a mature blood cell, whether it’s a red blood cell, a white blood cell such as a lymphocyte, or some other type of blood cell.
, hematopoiesis in the embryo produces only red blood cells that can provide developing organs with oxygen. At this stage in development, the yolk sac, which nourishes the embryo until the placenta.
James till, a biophysicist, and ernest mcculloch, a physician, pioneered the study of hematopoiesis in the early 1960s through their development of a quantitative spleen colony assay, establishment of a hematopoietic stem cell, and data analysis that yielded a stochastic model of hematopoiesis.
Two models for hematopoiesis have been proposed: determinism and stochastic theory. For the stem cells and other undifferentiated blood cells in the bone marrow, the determination is generally explained by the determinism theory of haematopoiesis, saying that colony stimulating factors and other factors of the haematopoietic microenvironment.
That growth factors control survival and proliferation of hematopoietic lineages and also transduce.
According to attachment theory, children differ in the kinds of strategies they use to regulate attachment-related anxiety. Following a separation and reunion, for example, some insecure children approach their parents, but with ambivalence and resistance, whereas others withdraw from their parents, apparently minimizing attachment-related.
A novel computer algorithm, or set of rules, that accurately predicts the orbits of planets in the solar system could be adapted to better predict and control the behavior of the plasma that fuels.
Sep 27, 2016 using hematopoietic stem cells as our model system, we discuss the have better theories of how stem cell (a)symmetric division is controlled,.
Hematopoiesis, mice, stochastic processes, transplantation, clonal hematopoiesis of indeterminate potential, umbilical cord blood introduction hematopoiesis is an intricate system of checks and balances assuring that hematopoietic stem cells (hscs) give rise to sufficient red blood cells, white blood cells, and platelets to maintain homeostasis.
Further information on automation and how to apply it can be found in our ebook: automation 101: an industry guide to control system engineering. For additional information on electrical engineering, please go to any of the following sources: ieee isa and electrical codes.
May 25, 2018 hematopoietic stem cell fate through metabolic control theories differ regarding the contributions of hscs to unperturbed homeostasis.
Hematopoiesis: types of haematopoietic stem cells, process and regulation haematopoiesis. Haematopoiesis is defined as the process of formation, development and differentiation of blood cells. The blood cells are formed from haematopoietic stem cells (hscs) which are either multipotent or pluripotent in nature.
Attentional control theory is an approach to anxiety and cognition representing a major development of eysenck and calvo's (1992) processing efficiency theory. It is assumed that anxiety impairs efficient functioning of the goal-directed attentional system and increases the extent to which processin.
Twenty-five years ago, the “superpredator” myth led nearly every state in the country to expand laws that removed children from juvenile courts and exposed them to adult sentences, including life without parole.
Hscs are adult stem cells that can differentiate into specialized blood cells that control immune function, homeostasis balance, and response to microorganisms.
The blood system is composed of hematopoietic and hemolytic organs, circulating blood, and the control apparatus, which plays the important role in hematopoiesis by a balanced production of spectacular moiety of the cellular elements.
Normal hematopoiesis is a well-regulated process in which the generation of mature blood elements occurs from a primitive pluripotent stem cell in an ordered sequence of maturation and proliferation. Regulation occurs at the level of the structured microenvironment (stroma), via cell-cell interactio.
Despite considerable success in characterizing hematopoiesis, crucial remaining questions include how stem and multipotent progenitor cells control the balance of symmetric and asymmetric differentiation, and how the system responds to perturbations, such as anemia, infection, or inflammation.
Clonal hematopoiesis (ch) describes an asymptomatic expansion of blood cells descended from a single hematopoietic stem cell. Recent studies have shown that ch increases in frequency with aging and is often driven by somatic mutations in genes that are recurrently mutated in hematologic malignancies. When ch is associated with a mutation in a leukemia-associated gene at a variant allele.
Nci's dictionary of cancer terms provides easy-to-understand definitions for words and phrases related to cancer and medicine.
This analysis helped develop the theory of hematopoiesis control describing the regularities in the work of basic subdivisions of the hematopoietic tissue under normal and pathological conditions, as well as the performance and interaction of the local and long-ranged control systems.
This paper is concerned with the generalized hematopoiesis model with discontinuous harvesting terms. Under the framework of filippov solution, by means of the differential inclusions and the topological degree theory in set-valued analysis, we have established the existence of the bounded positive periodic solutions for the addressed models.
Haematopoiesis (/hɪˌmætoʊpɔɪˈiːsɪs, ˈhiːmətoʊ-, ˌhɛmə-/, from greek αἷμα, 'blood' in stochastic theory, undifferentiated blood cells differentiate to specific cell types by randomness.
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In this paper, a generalized model of hematopoiesis with delays and impulses is considered. By employing the contraction mapping principle and a novel type of impulsive delay inequality, we prove.
Stochastic (from greek στόχος (stókhos) 'aim, guess') refers to the property of being well described by a random probability distribution. Although stochasticity and randomness are distinct in that the former refers to a modeling approach and the latter refers to phenomena itself, these two terms are often used synonymously.
This analysis helped develop the theory of hematopoiesis control describing the regularities in the work of basic subdivisions of the hematopoietic tissue under.
If hematopoiesis in the bone marrow becomes inadequate ( after excessive blood loss) the liver or spleen can initiate blood cell formation bone marrow is one of the largest organs of the body, comparable in total size to the liver (1500g).
Meaning and sites of hematopoiesis: hematopoiesis is the process by which immature precursor cells develop into mature blood cells. The currently accepted theory on how this process works is called the monophyletic theory which simply means that a single type of stem cell gives rise to all the mature blood cells in the body.
Normal hematopoiesis is a well-regulated process in which the generation of into the pathophysiology of human disease and provided a theoretical framework.
Mar 25, 2010 while graph theoretical models can be circular, bayesian networks neutrophil production and their exit.
Hematopoiesis is the process by which the body produces blood cells and current research endorses a theory of hematopoiesis called the monophyletic theory. The embryo until the placenta is fully developed, controls hematopoiesis.
May 29, 2018 extramedullary hematopoiesis (emh) in postnatal life is a pathological from the spleen of tamoxifen-treated tlx1creer-venus controls (ctr) and hematopoiesis: a new look at the underlying stem cell niche, theories.
2015 20th international conference on control systems and computer science, 611-617. (2015) a delay differential-difference system of hematopoietic stem cell dynamics.
Relate normal and abnormal hematopoiesis to the various organs involved in the hematopoietic process. Explain the stem cell theory of hematopoiesis, including the names of various stem cells and progenitor cells and their lineage associations.
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